Nicola Guerini was born in Verona. He studied Piano, Organ and Organ Composition, Conducting and Composition at the Conservatory C.Pollini, Padua and at the Conservatory G.Verdi, Milan; he then perfected his studies at the Accademia Chigiana, at the Mozarteum Salzburg, at the Accademia Pescarese with Donato Renzetti. In 2010 he achieved a Master of Arts in Music Conducting at Lugano Musikhochschule (Switzerland) with Giorgio Bernasconi and Arturo Tamayo. His début was at 24 as composer and conductor for the Fondazione Arena, Verona. He was assistant to Ralf Weikart, Giorgio Bernasconi and Donato Renzetti in Italy and international productions at Teatro alla Scala, Teatro dell’Opera Roma and Lyric Opera Chicago. He has taken part in festivals and prestigious concert seasons with important orchestras including the Orchestra Sinfonica di Roma, the Rousse Philharmonic Orchestra, the Targu Mures Philarmonia, the HRT Zagreb Orchestra, the Divertimento Ensemble, the Mozart Chamber Orchestra, the Ensemble ‘900 di Lugano, the ICARUS Ensemble, the Targu Mures Philarmonia Orchestra,  the Rousse Philharmonic Orchestra, I Virtuosi Italiani, Orchestra di Padovae del the Orquesta Sinfónica de la UANL di Monterrey, the Sofia Philarmonie, the Berliner Symphoniker and the PKF Prague Philarmonia. 
He is President of the "Peter Maag" Music Fund and artistic director of the lyric opera laboratory “La Bottega”, which revives Maag’s well-known workshop for young talents. He has founded Maria Callas International Competition and Maria Callas International Festival.